Clinical Manifestation Summary of Common Comorbidity Conditions Associated with ASD

Yinan Zheng

doi:10.62051/ijphmr.v6n6.10

Authors

Yinan Zheng College of Nursing, Shanxi University of Chinese Medicine, Jinzhong City, Shanxi Province, 030619, China

DOI:

https://doi.org/10.62051/ijphmr.v6n6.10

Keywords:

Autism spectrum disorder, Clinical manifestations, Psychiatric comorbidities, Epilepsy, Gastrointestinal symptoms, Sleep disorders

Abstract

Autism spectrum disorder is a heterogeneous neurodevelopmental disorder with problems in social communication and restricted or repetitive behaviours. However, there are often many other types of psychiatric diseases, neurological disorders, gastrointestinal diseases and sleep disorders in people who need help. List the main clinical features of frequent co-occurring disorders in autism in this paper. Psychiatric comorbidities, such as attention deficit hyperactivity disorder and anxiety disorders, may present as emotional dysregulation, impulsivity, avoidance behaviours and self-harm. Neurological diseases that cause repetitive movement disorders should be excluded first. Gastrointestinal disorders can be expressed indirectly, such as irritability, anger and poor sleep in children who are unable to communicate verbally. Sleep disorders will result in various mental and behaviour problems. Based on the above, it can be seen that the doctor should not assume autism is the cause of other diseases and disorders, but must also cooperate with other departments to conduct coordinated diagnosis and treatment.

References

[1] Lai, M. C., Lombardo, M. V., & Baron-Cohen, S. (2014). Autism. The Lancet, 383(9920), 896–910. https://doi.org/10.1016/S0140-6736(13)61546-1

[2] Simonoff, E., Pickles, A., Charman, T., Chandler, S., Loucas, T., & Baird, G. (2008). Psychiatric disorders in children with autism spectrum disorders: prevalence, comorbidity, and associated factors in a population-derived sample. Journal of the American Academy of Child & Adolescent Psychiatry, 47(8), 921–929. https://doi.org/10.1097/CHI.0b013e318179964f

[3] Matson, J. L., & Nebel-Schwalm, M. S. (2007). Comorbid psychopathology with autism spectrum disorder in children: An overview. Research in Developmental Disabilities, 28(4), 341–352. https://doi.org/10.1016/j.ridd.2006.05.002

[4] McElhanon, B. O., McCracken, C., Karpen, S., & Sharp, W. G. (2014). Gastrointestinal symptoms in autism spectrum disorder: a meta-analysis. Pediatrics, 133(5), 872–883. https://doi.org/10.1542/peds.2013-3443

[5] Tuchman, R., & Rapin, I. (2002). Epilepsy in autism. The Lancet Neurology, 1(6), 352–358. https://doi.org/10.1016/S1474-4422(02)00156-8

[6] Cortesi, F., Giannotti, F., Ivanenko, A., & Johnson, K. (2010). Sleep in children with autistic spectrum disorder. Sleep Medicine, 11(7), 659–664. https://doi.org/10.1016/j.sleep.2009.12.007

[7] Leyfer, O. T., Folstein, S. E., Bacalman, S., Davis, N. O., Dinh, E. T., Morgan, J., Tager-Flusberg, H., & Lainhart, J. E. (2006). Comorbid psychiatric disorders in children with autism: interview development and rates of disorders. Journal of Autism and Developmental Disorders, 36(7), 849–861. https://doi.org/10.1007/s10803-006-0109-2

[8] Gargaro, B. A., Rinehart, N. J., Bradshaw, J. L., Tonge, B. J., & Sheppard, D. M. (2011). Autism and ADHD: How Far Have We Come in the Comorbidity Debate? Neuroscience & Biobehavioral Reviews, 35(5), 1081–1088. https://doi.org/10.1016/j.neubiorev.2010.12.002

[9] Mannion, A., & Leader, G. (2013). Comorbidity in autism spectrum disorder: A literature review. Research in Autism Spectrum Disorders, 7(12), 1595–1616. https://doi.org/10.1016/j.rasd.2013.09.006

[10] Bauman, M. L. (2010). Medical Comorbidities in Autism: Challenges to Diagnosis and Treatment. Neurotherapeutics, 7(3), 320–327. https://doi.org/10.1016/j.neuptr.2010.04.004