Existing Therapeutic Vaccine Approaches for Cervical Cancer

Authors

  • Shuyang Liu

DOI:

https://doi.org/10.62051/3hn1sb95

Keywords:

cervical cancer; vaccines; treatment.

Abstract

As the level of modern medical treatment gradually advances and improves with the development, therapeutic vaccines are gradually being researched and applied in clinical treatment, but there are still some areas that require further research and improvement. This article summarizes the research progress, market development, awareness and popularity of cervical cancer therapeutic vaccines in recent years and treatment scope. The study found that the clinical basis for therapeutic vaccines and their popularity and awareness in remote and low-income developing countries are low, and people in these areas also have misunderstandings about cervical cancer. In addition, the cervical cancer therapeutic vaccine mainly targets HPV16 and HPV18, two subtypes that are the main factors causing cervical cancer. Therefore, there is basically no progress in the research of therapeutic vaccines for cervical cancer except for these two subtypes. The development of therapeutic vaccines for cervical cancer has gradually progressed, but in some places, there are still shortcomings compared with vaccines that are already on the market and are used proficiently.

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References

World Health Organization. Cervical Cancer. www.who.int/news-room/fact-sheets/detail/cervical-cancer.

World Health Organization. Cervical Cancer. www.who.int/health-topics/cervical-cancer#tab=tab_1.

Singh D, Vignat J, Lorenzoni V, et al. Global estimates of incidence and mortality of cervical cancer in 2020: a baseline analysis of the WHO Global Cervical Cancer Elimination Initiative. The Lancet Global Health, 2023, 11 (2): e197-e206.

Stenger, Matthew. “Balstilimab plus Zalifrelimab for the Second-Line Treatment of Advanced Cervical Cancer.” The ASCO Post, ascopost.com/news/january-2022/balstilimab-plus-zalifrelimab-for-the-second-line-treatment-of-advanced-cervical-cancer/.

A Study of Pembrolizumab (MK-3475) plus Platinum and Gemcitabine as First Line Treatment of Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma (Piper)-Full Text View. ClinicalTrials.Gov, classic.clinicaltrials.gov/ct2/show/study/NCT05286619.

Zhang S, Xu H, Zhang L, et al. Cervical cancer: Epidemiology, risk factors and screening. Chinese Journal of Cancer Research, 2020, 32 (6): 720.

Bogdanova A, Andrawos C, Constantinou C. Cervical cancer, geographical inequalities, prevention and barriers in resource depleted countries. Oncology letters, 2022, 23 (4): 1 - 11.

Pina-Sanchez P. Human Papillomavirus: Challenges and opportunities for the control of cervical cancer [J]. Archives of Medical Research, 2022.

Panwar K, Godi A, Cocuzza C E, et al. Binding antibody levels to vaccine (HPV6/11/16/18) and non-vaccine (HPV31/33/45/52/58) HPV antigens up to 7 years following immunization with either Cervarix® or Gardasil® vaccine. Vaccine, 2022, 40 (9): 1198 - 1202.

Schmidt M W, Battista M J, Schmidt M, et al. Efficacy and Safety of Immunotherapy for Cervical Cancer-A Systematic Review of Clinical Trials. Cancers, 2022, 14 (2): 441.

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Published

24-03-2024

How to Cite

Liu , S. (2024). Existing Therapeutic Vaccine Approaches for Cervical Cancer. Transactions on Materials, Biotechnology and Life Sciences, 3, 246-250. https://doi.org/10.62051/3hn1sb95