Advances in Ginseng Tissue Culture Research

Authors

  • Hongyan Jing

DOI:

https://doi.org/10.62051/y0rw9733

Keywords:

plant tissue culture; Panax ginseng C.A. Meyer; adventitious root; hairy root.

Abstract

Panax ginseng C.A. Meyer is a traditional and precious Chinese medicinal herb that is widely used in the fields of food, medicine, and cosmetics. This article provides a comprehensive overview of the research progress on Panax ginseng C.A. Meyer tissue culture from four aspects: the current utilization of Panax ginseng C.A. Meyer resources, Panax ginseng C.A. Meyer adventitious root culture, hairy root culture, and elicitor. The aim is to provide a reference for the rapid acquisition of secondary metabolites of Panax ginseng C.A. Meyer and promote the development and sustainable utilization of Panax ginseng C.A. Meyer resources.

Downloads

Download data is not yet available.

References

[1] FENG Y, MA F, WU E, et al. Ginsenosides: Allies of gastrointestinal tumor immunotherapy[J]. Front Pharmacol, 2022,13: 922029.

[2] KANG Z, ZHONGA Y, WU T, et al. Ginsenoside from ginseng: a promising treatment for inflammatory bowel disease[J]. Pharmacol Rep, 2021,73(3): 700-711.

[3] ZHANG J, AI Z, HU Y, et al. Remarkable impact of commercial sterilizing on ginsenosides transformation in fresh ginseng pulp based on widely targeted metabolomics analysis[J]. Food Chem X, 2022,15: 100415.

[4] CHEN S, WANG Z, HUANG Y, et al. Ginseng and anticancer drug combination to improve cancer chemotherapy: a critical review[J]. Evid Based Complement Alternat Med, 2014,2014: 168940.

[5] LI M X, WEI Q Q, LU H J. Progress on the Elucidation of the Antinociceptive Effect of Ginseng and Ginsenosides in Chronic Pain[J]. Front Pharmacol, 2022,13: 821940.

[6] NI B, SONG X, SHI B, et al. Research progress of ginseng in the treatment of gastrointestinal cancers[J]. Frontiers in Pharmacology, 2022,13.

[7] KIM H M, SONG Y, HYUN G H, et al. Characterization and Antioxidant Activity Determination of Neutral and Acidic Polysaccharides from Panax Ginseng C. A. Meyer[J]. Molecules, 2020,25(4).

[8] YANG S, LI F, LU S, et al. Ginseng root extract attenuates inflammation by inhibiting the MAPK/NF-κB signaling pathway and activating autophagy and p62-Nrf2-Keap1 signaling in vitro and in vivo[J]. J Ethnopharmacol, 2022,283: 114739.

[9] ALSAYARI A, MUHSINAH A B, ALMAGHASLAH D, et al. Pharmacological Efficacy of Ginseng against Respiratory Tract Infections[J]. Molecules, 2021,26(13).

[10] CHEN W, BALAN P, POPOVICH D G. Review of Ginseng Anti-Diabetic Studies[J]. Molecules, 2019,24(24).

[11] MA Y, LI J, MAI J, et al. Ginsenoside Rb2 exhibits therapeutic value for male osteoporosis in orchiectomy mice by suppressing osteoclastogenesis and modulating NF-κB/MAPK signaling pathways[J]. Food Funct, 2024,15(3): 1583-1597.

[12] HUANG J, LIU D, WANG Y, et al. Ginseng polysaccharides alter the gut microbiota and kynurenine/tryptophan ratio, potentiating the antitumour effect of antiprogrammed cell death 1/programmed cell death ligand 1 (anti-PD-1/PD-L1) immunotherapy[J]. Gut, 2022,71(4): 734-745.

[13] WANG N, WANG X, HE M, et al. Ginseng polysaccharides: A potential neuroprotective agent[J]. J Ginseng Res, 2021,45(2): 211-217.

[14] TIAN T, KO C N, LUO W, et al. The anti-aging mechanism of ginsenosides with medicine and food homology[J]. Food Funct, 2023,14(20): 9123-9136.

[15] HOU L, ZOU Z, WANG Y, et al. Exploring the anti-atherosclerosis mechanism of ginsenoside Rb1 by integrating network pharmacology and experimental verification[J]. Aging (Albany NY), 2024,16(8): 6745-6756.

[16] MA G D, CHIU C H, HSU Y J, et al. Changbai Mountain Ginseng (Panax ginseng C.A. Mey) Extract Supplementation Improves Exercise Performance and Energy Utilization and Decreases Fatigue-Associated Parameters in Mice[J]. Molecules, 2017,22(2).

[17] TONG A Z, LIU W, LIU Q, et al. Diversity and composition of the Panax ginseng rhizosphere microbiome in various cultivation modesand ages[J]. BMC Microbiol, 2021,21(1): 18.

[18] LIU C, JIANG Y, YUN Z, et al. Small RNA-Seq to Unveil the miRNA Expression Patterns and Identify the Target Genes in Panax ginseng[J]. Plants (Basel), 2023,12(17).

[19] ZHAO G, PEI Y, YANG R, et al. A non-destructive testing method for early detection of ginseng root diseases using machine learning technologies based on leaf hyperspectral reflectance[J]. Front Plant Sci, 2022,13: 1031030.

[20] LI X, CHEN Y, LAI Y, et al. Sustainable Utilization of Traditional Chinese Medicine Resources: Systematic Evaluation on Different Production Modes[J]. Evid Based Complement Alternat Med, 2015,2015: 218901.

[21] FEHER A. Callus, Dedifferentiation, Totipotency, Somatic Embryogenesis: What These Terms Mean in the Era of Molecular Plant Biology?[J]. Front Plant Sci, 2019,10: 536.

[22] THORPE T A. History of plant tissue culture[J]. Mol Biotechnol, 2007,37(2): 169-180.

[23] NOBÉCOURT, PIERRE. La culture des tissus végétaux[J]. Bulletin De La Socit Botanique De France, 2014,104(9): 623-665.

[24] LAIMER M, RÜCKER W. Plant Tissue Culture 100 years since Gottlieb Haberlandt /[M]. Plant tissue culture : 100 years since Gottlieb Haberlandt, 2003.

[25] ALTMAN A. Plant tissue culture and biotechnology: perspectives in the history and prospects of the International Association of Plant Biotechnology (IAPB )[J]. IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-PLANT, 2019,55(5): 590-594.

[26] ROBBINS W J. Cultivation of Excised Root Tips and Stem Tips Under Sterile Conditions[J]. Botanical Gazette, 1922,73(5): 376-390.

[27] ROBBINS W J. Effect of Autolized Yeast and Peptone on Growth of Excised Corn Root Tips in the Dark[J]. Botanical Gazette, 1922,74(1): 59-79.

[28] WHITE P R. Potentially Unlimited Growth of Excised Tomato Root Tips in a Liquid Medium[J]. Plant Physiology, 1934,9(3): 585-600.

[29] BALL E A. DEVELOPMENT IN STERILE CULTURE OF STEM TIPS AND SUBJACENT REGIONS OF TROPAEOLUM MAJUS L. AND OF LUPINUS ALBUS L[J]. American Journal of Botany, 1946,33: 301-318.

[30] DAGLA H. Plant tissue culture[J]. Resonance, 2012,17.

[31] SKOOG F, MILLER C O. Chemical regulation of growth and organ formation in plant tissues cultured in vitro[J]. Symposia of the Society for Experimental Biology, 1957,11: 118-130.

[32] HÖXTERMANN E. Cellular ‘elementary organisms’ in vitro. The early vision of Gottlieb Haberlandt and its realization[J]. Physiologia Plantarum, 1997,100(3): 716-728.

[33] KRIKORIAN A D, BERQUAM D L. Plant cell and tissue cultures: The role of Haberlandt[J]. The Botanical Review, 1969,35(1): 59-67.

[34] STEWARD F C, MAPES M O, MEARS K E. GROWTH AND ORGANIZED DEVELOPMENT OF CULTURED CELLS. II. Organization in Cultures Grown from Freely Suspended Cell[J]. American Journal of Botany, 1958,45: 705-708.

[35] REINERT J. Über die Kontrolle der Morphogenese und die Induktion von Adventivembryonen an Gewebekulturen aus Karotten[J]. Planta, 1959,53(4): 318-333.

[36] BACKS-HÜSEMANN D, REINERT J. Embryobildung durch isolierte Einzelzellen aus Gewebekulturen vonDaucus carota[J]. Protoplasma, 1970,70(1): 49-60.

[37] LIU X, ZHANG P, ZHAO Q, et al. Making small molecules in plants: A chassis for synthetic biology-based production of plant natural products[J]. Journal of Integrative Plant Biology, 2023,65(2): 417-443.

[38] RAMEZANNEZHAD R, BOJNOORDI M M, ARMIN M, et al. Artificial neural network modeling to predict and optimize phenolic acid production from callus culture of Lactuca undulata Ledeb.[J]. In Vitro Cellular & Developmental Biology - Plant, 2022,58(4): 653-663.

[39] JI B, XUAN L, ZHANG Y, et al. Application of Data Modeling, Instrument Engineering and Nanomaterials in Selected Medid the Scientific Recinal Plant Tissue Culture[J]. Plants, 2023,12(7): 1505.

[40] SINGH R, AHAMAD S. Integration of Nanotechnology in Plant Tissue Culture[J]. CURRENT NANOSCIENCE, 2022,18(5): 604-610.

[41] HUSSAIN M J, ABBAS Y, NAZLI N, et al. Root Cultures, a Boon for the Production of Valuable Compounds: A Comparative Review[J]. Plants (Basel), 2022,11(3).

[42] ABBASPOUR J, EHSANPOUR A A, AGHAEI M, et al. Sesquiterpene lactones from shoot culture of Artemisia aucheri with cytotoxicity against prostate and breast cancer cells[J]. Res Pharm Sci, 2019,14(4): 329-334.

[43] LIU J, CHEN T, ZHANG J, et al. Ginsenosides regulate adventitious root formation in Panax ginseng via a CLE45–WOX11 regulatory module[J]. Journal of Experimental Botany, 2020,71(20): 6396-6407.

[44] WANG S, LIANG W, YAO L, et al. Effect of temperature on morphology, ginsenosides biosynthesis, functional genes, and transcriptional factors expression in Panax ginseng adventitious roots[J]. J Food Biochem, 2019,43(4): e12794.

[45] XU B, WANG X, WU Z, et al. Identification of ginsenoside components from adventitious root of ginseng and their hypoglycemic effects on T1DM mice: A network pharmacology and animal experiment study[J]. Journal of Functional Foods, 2024,116: 106083.

[46] WOODS R R, GEYER B C, MOR T S. Hairy-root organ cultures for the production of human acetylcholinesterase[J]. BMC Biotechnol, 2008,8: 95.

[47] ALCALDE M A, HIDALGO-MARTINEZ D, BRU M R, et al. Insights into enhancing Centella asiatica organ cell biofactories via hairy root protein profiling[J]. Front Plant Sci, 2023,14: 1274767.

[48] BULGAKOV V P, KHODAKOVSKAYA M V, LABETSKAYA N V, et al. The impact of plant rolC oncogene on ginsenoside production by ginseng hairy root cultures[J]. Phytochemistry, 1998,49(7): 1929-1934.

[49] Van BINH N, KIM M J, GIANG V N L, et al. Improved biomass and metabolite production in hairy root culture in various genotypes of Panax ginseng through genetic transformation[J]. Plant Cell, Tissue and Organ Culture (PCTOC), 2023,156(2): 43.

[50] ZHOU T, LI Q, HUANG X, et al. Analysis Transcriptome and Phytohormone Changes Associated with the Allelopathic Effects of Ginseng Hairy Roots Induced by Different-Polarity Ginsenoside Components[J]. Molecules, 2024,29(8): 1877.

[51] KOCHAN E, SZYMCZYK P, KUŹMA A, et al. Yeast Extract Stimulates Ginsenoside Production in Hairy Root Cultures of American Ginseng Cultivated in Shake Flasks and Nutrient Sprinkle Bioreactors[J]. Molecules, 2017,22(6).

[52] WANG S, WANG J, LIANG W, et al. Promotion of ginsenosides production in a co-cultivation system of Panax ginseng adventitious roots and immobilized Aspergillus niger[J]. Industrial Crops and Products, 2019,140: 111564.

[53] SONG X, WU H, YIN Z, et al. Endophytic Bacteria Isolated from Panax ginseng Improves Ginsenoside Accumulation in Adventitious Ginseng Root Culture[J]. Molecules, 2017,22(6): 837.

[54] ] AN X L, YU Y, FAN M Z, et al. A fungal mycelium elicitor efficiently improved ginsenoside synthesis during adventitious root culture of Panax ginseng[J]. Journal of Plant Biochemistry and Biotechnology, 2022,31(3): 657-664.

[55] LI J, YUAN Y, JIANG W, et al. Abscisic acid is required for cold-induced accumulation of ginsenosides Rg1 and Re in Panax ginseng adventitious roots[J]. Plant Cell, Tissue and Organ Culture (PCTOC), 2022,149(1): 325-333.

Downloads

Published

29-09-2024

How to Cite

Jing, H. (2024). Advances in Ginseng Tissue Culture Research. Transactions on Materials, Biotechnology and Life Sciences, 6, 58-64. https://doi.org/10.62051/y0rw9733