Research Progress on Antimicrobial Surface Modification Materials for Dental Implants

Fei Meng; Yang Chen

doi:10.62051/ijphmr.v4n3.02

Authors

Fei Meng
Yang Chen

DOI:

https://doi.org/10.62051/ijphmr.v4n3.02

Keywords:

Peri-implantitis, Implants, Antimicrobial

Abstract

Peri-implantitis is one of the main reasons for the failure of dental implants. Traditional implant surfaces lack antimicrobial properties and are prone to bacterial infections. In recent years, antimicrobial surface modification technologies for implants have become a research hotspot. These technologies endow implants with antimicrobial functions through physical, chemical, or biological methods to improve long-term success rates. This paper reviews the main strategies for antimicrobial surface modification of implants (such as antimicrobial coatings, nanostructural modifications, ion doping, and bioactive molecule loading), analyzes the advantages and disadvantages of different methods, and explores future development directions to provide a theoretical basis for the design of clinical implants.

References

[1] Wang M, Jiang X, Wu C, et al. Application of hyaluronic acid in dental tissue regeneration [J]. Journal of biomedical materials research. Part A, 2018, 106(4): 996-1002.

[2] Tsukada Y, Nakamura R, Akazawa K, et al. Hyaluronic acid promotes epithelial migration during wound healing in vitro [J]. Journal of periodontology, 2019, 90(7): 784-792.

[3] Vignesh R, Sudhakar U, Uma K. Role of Platelet rich fibrin and hyaluronic acid in surgical management of endo-periodontal lesion: A case report [J]. Journal of oral biology and craniofacial research, 2020, 10(1): 115-118.

[4] Sydiskis R, Owen D G, Lohr J L, et al. Inactivation of enveloped viruses by anthraquinones extracted from plants [J]. Antimicrobial agents and chemotherapy, 1991, 35(12): 2463-2466.

[5] Hocevar B J, Mohoric L, Kos J. Hyaluronan modulates TRAIL-resistance in colon cancer cells through STAT3 activation [J]. Experimental cell research, 2012, 318(2): 117-125.