Research Progress on Multimodal Analgesia for Preventing Postoperative Pain Following Extraction of Impacted Mandibular Third Molars
DOI:
https://doi.org/10.62051/ijphmr.v4n1.04Keywords:
Painmanagement, Pain assessment, Pharmacological treatment, Non-pharmacological treatmentAbstract
Pain, as a common complication after the extraction of impacted mandibular third molars, significantly affects patients' physiological functions, social activities, and psychological well-being. Given that traditional analgesic methods are often accompanied by numerous side effects, multimodal analgesia strategies have emerged and gained widespread advocacy. This strategy involves precise pain assessment and the combined use of multiple analgesic drugs with different mechanisms of action, along with non-pharmacological treatments, aiming to achieve optimal pain relief while minimizing adverse reactions. This article reviews the pain assessment methods, non-pharmacological treatments, and pharmacological regimens within the multimodal analgesia strategy, with the goal of providing scientific evidence and practical guidance for pain management in patients undergoing impacted mandibular third molar extraction.
References
[1] TEAM P P. Perioperative Quality Improvement Programme-Annual Report 2018-19 [J]. 2019.
[2] SERRA S, SPAMPINATO M D, RICCARDI A, et al. Pain Management at the End of Life in the Emergency Department: A Narrative Review of the Literature and a Practical Clinical Approach [J]. J Clin Med, 2023, 12(13).
[3] SISK A L, HAMMER W B, SHELTON D W, et al. Complications following removal of impacted third molars: the role of the experience of the surgeon [J]. J Oral Maxillofac Surg, 1986, 44(11): 855-9.
[4] QUESADA-BRAVO F J, GARCíA-CARRICONDO A R, ESPíN-GáLVEZ F, et al. Comparative Study between the Combination of Dexamethasone and Bupivacaine for Third Molar Surgery Postoperative Pain: A Triple-Blind, Randomized Clinical Trial [J]. J Clin Med, 2021, 10(21).
[5] SHIRZADEH A, BAGHERI SHIRVAN S, ALIZADEH O, et al. What is the Most Prevalent Type of Third Molar Impaction in Patients with Pericoronitis? [J]. World J Plast Surg, 2023, 12(2): 57-63.
[6] LODI G, AZZI L, VARONI E M, et al. Antibiotics to prevent complications following tooth extractions [J]. Cochrane Database Syst Rev, 2021, 2(2): Cd003811.
[7] O'NEILL A, LIRK P. Multimodal Analgesia [J]. Anesthesiol Clin, 2022, 40(3): 455-68.
[8] MIROSHNYCHENKO A, IBRAHIM S, AZAB M, et al. Acute Postoperative Pain Due to Dental Extraction in the Adult Population: A Systematic Review and Network Meta-analysis [J]. J Dent Res, 2023, 102(4): 391-401.
[9] MOORE P A, DIONNE R A, COOPER S A, et al. Why do we prescribe Vicodin? [J]. J Am Dent Assoc, 2016, 147(7): 530-3.
[10] SUDA K J, ZHOU J, ROWAN S A, et al. Overprescribing of Opioids to Adults by Dentists in the U.S., 2011-2015 [J]. Am J Prev Med, 2020, 58(4): 473-86.
[11] KIM S H, KIM S, KIM Y S, et al. Application of sequential multimodal analgesia before and after impacted mandibular third molar extraction: Protocol for a randomized controlled trial [J]. Contemp Clin Trials Commun, 2023, 32: 101078.
[12] BUVANENDRAN A, KROIN J S. Multimodal analgesia for controlling acute postoperative pain [J]. Curr Opin Anaesthesiol, 2009, 22(5): 588-93.
[13] DE SOUZA R L P, SR., ABRãO J, GARCIA L V, et al. Impact of a Multimodal Analgesia Protocol in an Intensive Care Unit: A Pre-post Cohort Study [J]. Cureus, 2022, 14(3): e22786.
[14] BIELEWICZ J, DANILUK B, KAMIENIAK P. VAS and NRS, Same or Different? Are Visual Analog Scale Values and Numerical Rating Scale Equally Viable Tools for Assessing Patients after Microdiscectomy? [J]. Pain Res Manag, 2022, 2022: 5337483.
[15] HJERMSTAD M J, FAYERS P M, HAUGEN D F, et al. Studies comparing Numerical Rating Scales, Verbal Rating Scales, and Visual Analogue Scales for assessment of pain intensity in adults: a systematic literature review [J]. J Pain Symptom Manage, 2011, 41(6): 1073-93.
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