Pleomorphic Adenoma of the parotid gland: A Case Report

Abstract

Objective: to report a case of left parotid adenocarcinoma in pleomorphic adenoma in order to improve the understanding of the disease. Methods: the clinical characteristics, clinical manifestations and risk factors of a case of left parotid adenocarcinoma in pleomorphic adenoma were analyzed. Results: clinical characteristics: the patient had a long clinical course and was diagnosed as"eft parotid gland cancer in pleomorphic adenoma", in which the cancer component was considered as adenoid cystic carcinoma, and the cancer tissue accounted for about 90%. Immunohistochemical results: CK (+), S-100 (+), CK5 / 6 (+), CK8 / 18 (+), CD117 (-), p63 (+), p53 (partial +, wild-type expression pattern), ab (+), CK7 (partial +), CK19 (partial +), Ki-67 index 30%. Conclusion:. Adenoid cystic carcinoma is easy to be missed and misdiagnosed due to its asymptomatic clinical features in the early stage. The lesion is easy to spread along the nerve, has strong invasion, has no boundary with surrounding tissues, and is easy to metastasize to the blood tract. Pathology combined with immunohistochemistry is the gold standard for diagnosis. The main treatment was surgical resection with close follow-up after operation.