The diversity of clinical features of depressive disorders and their diagnostic challenges

Xuyu Chen

doi:10.62051/tfy16r18

Authors

Xuyu Chen

DOI:

https://doi.org/10.62051/tfy16r18

Keywords:

depression disorder; Clinical characteristics; diagnosis.

Abstract

Depression disorder, a mental illness characterized by persistent low mood, has a variety of symptoms, including emotional, cognitive, physiological and behavioral manifestations. However, the non-specificity of these symptoms, the differences in subjective feelings of patients, the influence of sociocultural factors, and the concealment of patients all pose challenges for the accurate diagnosis of depressive disorders. This paper discusses the clinical characteristics of depressive disorder and the challenges faced in the diagnosis process, and puts forward coping strategies and suggestions, such as detailed medical history inquiry, comprehensive physical examination, the use of standardized rating scales, and the improvement of doctors' cognition and diagnostic ability, so as to improve the diagnostic accuracy of depressive disorder and provide patients with more accurate treatment plans.

Downloads

Download data is not yet available.

References

Kader E A T A, Vianney P, Kenneth C, et al. Major Depressive Disorder and Oxidative Stress: A Review of Peripheral and Genetic Biomarkers According to Clinical Characteristics and Disease Stages. [J]. Antioxidants (Basel, Switzerland), 2023, 12 (4).

Liao M Q, Zhang J Z, Yang X, et al. Changes of structural functional connectivity coupling and its correlations with cognitive function in patients with major depressive disorder [J]. Journal of Affective Disorders, 2024, 351 259-267.

Fang C, Mei Y, Yuqi C, et al. Correlation analysis of monocyte chemoattractant protein-1 and clinical characteristics and cognitive impairment in type 2 diabetes mellitus comorbid major depressive disorder. [J]. Frontiers in aging neuroscience, 2023, 15 1081393-1081393.

Xianzhi S, Lili Y, Yingying Z, et al. Clinical characteristics of suicidal behavior in first hospitalization and drug-naïve patients with major depressive disorder. [J]. Annals of general psychiatry, 2023, 22 (1): 51-51.

Ayushi S, Anjana G. Inflammatory cytokines in rheumatoid arthritis: Diagnostic Challenges, Pathogenic Mechanisms and their role in depression and management. [J]. Current topics in medicinal chemistry, 2023, 23 (27): 2535-2551.

Kangcheng W, Xingyan L, Xiaotong W, et al. In vivo analyses reveal hippocampal subfield volume reductions in adolescents with schizophrenia, but not with major depressive disorder. [J]. Journal of psychiatric research, 2023, 165 56-63.

Conway R C, Aaronson T S, Sackeim A H, et al. Clinical characteristics and treatment exposure of patients with marked treatment-resistant unipolar major depressive disorder: A RECOVER trial report. [J]. Brain stimulation, 2024, 17 (2): 448-459.

Cristina F P, Alina J, Simona G T, et al. Challenges in Cerebral Venous Thrombosis Management—Case Reports and Short Literature Review [J]. Life, 2023, 13 (2): 334-334.

Yao Z, Tianming H, Ruolin L, et al. Distinct resting-state effective connectivity of large-scale networks in first-episode and recurrent major depression disorder: evidence from the REST-meta-MDD consortium. [J]. Frontiers in neuroscience, 2023, 17 1308551-1308551.

Yulug B, Ayyildiz S, Sayman D, et al. The functional role of the pulvinar in discriminating between objective and subjective cognitive impairment in major depressive disorder. [J]. Alzheimer's & dementia (New York, N. Y.), 2024, 10 (1): e12450-e12450.

CătălinaElena I, Costinel C P, Mihaela A, et al. Depression in Rheumatoid Arthritis: A Narrative Review-Diagnostic Challenges, Pathogenic Mechanisms and Effects. [J]. Medicina (Kaunas, Lithuania), 2022, 58 (11): 1637-1637.

Anusuiya N, Mina B, P. A H. Dementia Syndrome of Depression: Diagnostic Challenges and Clinical Relevance [J]. FOCUS, 2021, 19 (3): 308-310.

Ayushi S, Anjana G. Inflammatory cytokines in rheumatoid arthritis: Diagnostic Challenges, Pathogenic Mechanisms and their role in depression and management. [J]. Current topics in medicinal chemistry, 2023, 23 (27): 2535-2551.